the nutty professor 1996 film
Grossly overweight Prof. Sherman Klump, desperate to lose weight takes a special chemical that turns him into the slim but obnoxious Buddy Love.
Director: Tom Shadyac
Cast: Eddie Murphy, Jada Pinkett Smith, James Coburn, Larry Miller, Dave Chappelle, John Ales, Patricia Wilson, Jamal Mixon, Nichole McAuley, Hamilton von Watts, Chao Li Chi, Tony Carlin, Quinn Duffy, Montell Jordan, Doug Williams